The Main Culprits:
Existence of Congeners and Changes in Cytokines’ Concentration
The last two suspects are the main culprits causing your hangover.
In the alcohol that you consume, there are other compounds other than ethanol, known as congeners, and it includes methanol. Methanol breaks down to form Methanal (a toxic formaldehyde) and lastly to Methanoic acid (a formic acid). Congeners are then causing the severity of hangover to rise.
Lastly, our immune system is naturally affected by cytokines, which are small proteins released by cells affecting other cells. Drinking alcohol alters the concentration of cytokines, particularly IL-10, IL-12 and IFN-y, affecting the immune system. Researchers have found that the effects of this change is similar to those of hangover and thus, it affirms their role as the main culprit of hangover.
You have finally reached the last part of the series, hope this will give some enlightenment with regards to a hangover.
Book your IV slot now before the attack comes from those chemicals!